NPR Staff

A military assessment suggests a U.S. Tomahawk cruise missile was responsible for at least 165 deaths at an Iranian girls' school, according to a U.S. official who was not authorized to speak publicly.

The Iran war ground through 12th day as uncertainty grew over when it might end, amid continued attacks, a mounting human toll and concerns over the economic and energy impacts.

More than a week of the U.S. and Israel's war against Iran has dragged in global powers, upended the world's energy and transport sectors, and brought chaos to usually peaceful areas of the region.

Defense Secretary Pete Hegseth said the Pentagon was giving President Trump "maximum options" and that the war will not be "endless," a day after the president gave mixed signals about progress.

The Pentagon said a Space Brigade sergeant was killed and the price of oil increased after Iran named Mojtaba Khamenei as supreme leader and then launched new attacks at Israel and Gulf states.

Iran selected Mojtaba Khamenei as the new supreme leader. He is the son of the previous supreme leader. Also on Sunday, the U.S. announced the death of a seventh service member in the war.

Iran's foreign minister rejected the idea of a ceasefire or new talks with the Trump administration, and said Iran is prepared for the possibility of a U.S. ground invasion.

The U.S. and Israel say they conducted new strikes inside Iran overnight, targeting ballistic missile launchers. Iran claims it struck a U.S. oil tanker in the northern Persian Gulf.

Mifepristone is facing another major legal challenge.

Israel's military said it had begun a "broad wave of strikes" in Tehran on Wednesday morning. U.S. officials touted early gains, while Democrats warned the war could widen.